| Autor: |
de Leenheer, Els M.R., Kuijpers-Jagtman, Anne-Marie, Sengers, Rob C.A., Oudesluijs, Grétel G., Rappold, Gudrun A., Cremers, Cor W.R.J. |
| Předmět: |
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| Zdroj: |
Annals of Otology, Rhinology & Laryngology; Feb2003, Vol. 112 Issue 2, p153, 6p |
| Abstrakt: |
Conductive hearing loss was detected in a boy with a previous diagnosis of dyschondrosteosis. Dyschondrosteosis is a rare inherited condition characterized by mesomelic dwarfism and Madelung's deformity. The syndrome can be caused by mutations in the SHOX gene, and in that case, the pattern of inheritance is pseudoautosomal dominant. Indeed, SHOX mutation analysis in our patient revealed a deletion. The combination of dyschondrosteosis and conductive hearing loss has been reported in 2 previous cases. In our patient, exploratory tympanotomy revealed ankylosis of the stapes and a malformed incus. A substantial gain in hearing threshold was obtained by a stapedectomy in combination with a malleovestibulopexy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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