| Autor: |
Ferrer, Elena, Podzamczer, Daniel, Arnedo, Mireia, Fumero, Emilio, McKenna, Paula, Rinehart, Alex, Pérez, Joseé L., Barbeŕ, Maria J., Pumarola, Tomás, Gatell, José M., Gudiol, Francisco |
| Předmět: |
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| Zdroj: |
Journal of Infectious Diseases; 2/15/2003, Vol. 187 Issue 4, p687-690, 4p |
| Abstrakt: |
For the 127 Spanish patients enrolled in the Combine Study, a resistance substudy was performed with 100 (79%) plasma samples obtained at baseline and with 18 samples obtained from 19 patients at the time they experienced treatment failure. At baseline, primary mutations to nonnucleoside reverse-transcriptase inhibitors and protease inhibitors were not detected, whereas mutations to nucleoside reverse-transcriptase inhibitors were observed in 10% of patients. At failure, mutations were detected in 7 of 16 patients. An agreement in the results of virtual and real phenotypes was observed in the 93 samples in which both tests were performed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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