| Autor: |
Yu, PK, Yu, DY, Alder, VA, Su, EN, Cringle, SJ |
| Zdroj: |
Australian & New Zealand Journal of Ophthalmology; 1998, Vol. 26 Issue S1, pS53-S55, 3p |
| Abstrakt: |
Purpose: To determine whether the arrangement of microfilaments in retinal vascular endothelium is altered in early diabetes. Methods: F-actin and nuclei of retinal vascular endothelial cells of normal and diabetic (28 weeks postinduction) rats were examined using confocal microscopy. Results: An increase in the incidence of aberrant F-actin bundle arrangement in the diabetic retinal arteriole was observed, but there was no disruption of peripheral border F-actin. The diameter of superficial capillaries was increased in diabetic rats. Conclusion: These changes may be related to the endothelial dysfunction demonstrated in a previous pharmacological study. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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