Discovery of altered pharmacokinetics of CGP 15 210 G in poor hydroxylators of debrisoquine during early drug development.
| Autor: | Gleiter, CH, Aichele, G, Nilsson, E, Hengen, N, Antonin, KH, Bieck, PR |
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| Zdroj: | British Journal of Clinical Pharmacology; 1985, Vol. 20 Issue 1, p81-84, 4p |
| Abstrakt: | The pharmacokinetics of CGP 15 210 G, a new 5-HT uptake inhibitor in poor and extensive metabolisers of debrisoquine, give indirect evidence of an association between its metabolism and polymorphic hydroxylation of the debrisoquine type. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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