New antiviral strategy using capsid-nuclease fusion proteins.
| Autor: | Natsoulis, G., Boeke, J.D. |
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| Zdroj: | Nature; 8/15/1991, Vol. 352 Issue 6336, p632, 4p, 6 Black and White Photographs, 5 Diagrams, 1 Chart, 2 Graphs |
| Abstrakt: | Describes a new approach to interfering with viral replication in which a nuclease is fused to a capsid component so that the nuclease is encapsidated inside the virion where it can inactivate viral nucleic acid. Methods; Results; Discussion. |
| Databáze: | Complementary Index |
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