Sumatriptan and cerebral perfusion in healthy volunteers.

Autor: Scott, AK, Grimes, S, Ng, K, Critchley, M, Breckenridge, AM, Thomson, C, Pilgrim, AJ
Zdroj: British Journal of Clinical Pharmacology; 1992, Vol. 33 Issue 4, p401-404, 4p
Abstrakt: 1. The effect of sumatriptan on regional cerebral perfusion was studied in healthy volunteers. 2. Intravenous sumatriptan (2 mg) had no detectable effect on regional cerebral perfusion as measured using a SPECT system with 99technetiumm labelled hexemethylpropyleneamineoxime. 3. Sumatriptan had no effect on pulse, blood pressure or ECG indices. 4. All six volunteers experienced minor adverse effects during the intravenous infusion. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index