The effect of once daily beta-adrenoceptor blocker-thiazide diuretic combination on the ambulatory blood pressure.

Autor: Gould, BA, Hornung, RS, Kieso, H, Mann, S, Raftery, EB
Zdroj: British Journal of Clinical Pharmacology; 1982, Vol. 14 Issue 6, p827-831, 5p
Abstrakt: 1 We have assessed the efficacy of Viskaldix, a combination of pindolol 10 mg and clopamide 5 mg using continuous intra-arterial ambulatory blood pressure monitoring. 2 Fourteen of the sixteen patients entered were studied on no therapy and following a minimum of 6 weeks at a constant dosage of Viskaldix. 3 Viskaldix produced a marked and consistent reduction of the blood pressure over the 24 h. The diurnal variation in the heart rate was decreased. 4 The results were compared with those of a similar study with once-daily pindolol where there was control during the day but not in the early morning when the blood pressures rose rapidly. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index