Effects of salbutamol, ipratropium bromide and disodium cromoglycate on breathlessness induced by exercise in normal subjects.

Autor: Stark, RD, Gambles, SA
Zdroj: British Journal of Clinical Pharmacology; 1981, Vol. 12 Issue 4, p497-501, 5p
Abstrakt: 1 Healthy volunteers undertook submaximal graded exercise while objective measurements of cardio-respiratory function were made and breathlessness was assessed with serial visual analogue scales. 2 A useful and consistent relationship existed between breathlessness and ventilation for individual subjects. 3 Drugs were examined in this system to test whether they modified the relationship between ventilation and breathlessness such that less breathlessness occurred for a given level of ventilation. 4 Salbutamol, ipratropium bromide and disodium cromoglycate given by inhalation did not reduce breathlessness in healthy subjects during exercise. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index