Drug metabolism and liver function after methyldopa withdrawal.

Autor: Ylikallio, A, Sotaniemi, EA
Zdroj: British Journal of Clinical Pharmacology; 1980, Vol. 10 Issue 2, p115-119, 5p
Abstrakt: 1 The effects of methyldopa withdrawal on liver function and drug metabolism were investigated in ten elderly females suffering from the drug-induced orthostatic reaction and resistant hypertension. 2 There was a significant increase in serum albumin level, antipyrine metabolism and urinary excretion of D-glucaric acid 6 months after the methyldopa withdrawal. 3 The results suggest that patients treated with methyldopa might show a reduced metabolizing ability in spite of normal liver function tests. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index