Leukocyte Infiltration and Collagenolysis in Cervical Tissue from Intrapartum Sheep.

Autor: Luque, E. H., Bassani, M. M., Ramos, J. G., Maffini, M., Canal, A., Kass, L., Caldini, E. G., Jr, J. M. C. Ferreira, Toro, M. Muñoz de, Montes, G. S.
Zdroj: Journal of Veterinary Medicine Series A; 1997, Vol. 44 Issue 1-10, p501-510, 10p
Abstrakt: Sheep uterine cervices and cervical mucus were heavily infiltrated by neutrophils during labour, whereas samples of cervices obtained from non-pregnant controls had no infiltrate. The neutrophilic infiltrate of the sheep uterine cervix at term was not homogeneously distributed throughout the organ: luminal mucus contained more neutrophils than tissues which, in turn, displayed a differential distribution, the superficial subepithelial layer being more heavily infiltrated than the deeper submucous layers. A widespread collagenolysis was observed in the sheep uterine cervix at term. The homogeneous morphological aspect of degradation of collagen fibres throughout the whole cervical stroma contrasted with the above-mentioned differential distribution of neutrophils. On the basis of previous reports showing that collagenolysis follows the leukocytic invasion of human and rat cervices at term, a possible role for the neutrophilic infiltrate of the sheep uterine cervix is discussed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index