| Autor: |
Denié, Cécile, Vachiéry, Florence, Gadano, Adrian, Sogni, Philippe, Elman, Annie, Moreau, Richard, Valla, Dominique, Lebrec, Didier |
| Zdroj: |
Liver; 1998, Vol. 18 Issue 4, p239-244, 6p |
| Abstrakt: |
ABSTRACT- Aims/Backgrounds: The aim of this prospective study was to evaluate the influence of transjugular portosystemic intrahepatic shunts (TIPS) on tissue oxygenation in patients with cirrhosis and refractory ascites. Methods: Five shunted patients were included in the study. The blood and tissue oxygenation values were analyzed 12 days and 4 months after TIPS procedure. The results were compared with those observed in patients treated by paracentesis. Results: Unlike patients treated by paracentesis, PaO2 values remained unchanged throughout follow-up in shunted patients. After the TIPS procedure, there was a transient increase in systemic O2 transport and O2 uptake and a transient decrease in O2 saturation of hepatic oxyhemoglobin. After 4 months, TIPS resulted in an increase in PCO2 values and bicarbonate concentrations. Conclusions: The TIPS procedure seems to prevent the decrease in PaO2 observed in patients treated by paracentesis and may improve the respiratory alkalosis of cirrhosis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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