B-N-acetyl hexosaminidase (B-NAH) serum levels after endotoxin administration into the portal vein in the rat.

Autor: Scapa, E., Orda, R., Neuman, M., Sayfan, J., Abramovici, J., Eshchar, J.
Zdroj: Liver; 1991, Vol. 11 Issue 1, p39-41, 3p
Abstrakt: ABSTRACT- Endotoxin was injected directly into the portal vein in rats with and without common bile duct (CBD) ligation. B-N-acetyl hexosaminidase (B-NAH) activity levels in the serum were found to be significantly elevated 24 h later in both groups. Serum bile acid levels were found to be significantly higher in the endotoxin-injected groups of rats compared to controls. Thus, endotoxin, as well as bile acids, may cause damage to Kupffer cell membranes, resulting in accumulation of B-NAH in rat serum. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index