Abstrakt: |
This report deals with the survival and failures of 50 patients with malignancies of the maxillary sinus. The clinical, surgical, pathology, and survival characteristics of this series are tabulated, using the TNM classification system. Forty-one patients in the group had epidermoid cancers. The overall four-year survival of the patients in this series is 34 percent. The following is a breakdown of survival according to the TNM classification. 1. T-1 (eight patients) 85.7 percent 2. T-2 (five patients) 100.0 percent 3. T-3 (six patients) 50.0 percent 4. T-4, including those with nodes and distant metastases (31 patients) 4.0 percent Local recurrence was the major cause of treatment failure in this series. An analysis of the local recurrence failures, correlating the surgical pathology with the clinical classification, demonstrates that the advanced lesions (T-3 and T-4) and poorly differentiated tumors have the greatest chance of local recurrence. It is recommended that the latter group of cases receives an aggressive course of postoperative radiotherapy based on detailed pathology evaluation of the resected specimen. The liberal use of drainage procedures, radiotherapy, and cryotherapy for palliation is suggested. [ABSTRACT FROM AUTHOR] |