Redox approaches derived Tin (IV) oxide nanoparticles/graphene nanocomposites as the near-infrared absorber for selective human prostate cancer cells destruction.

Autor: Jin-Sheng Cheng, Qingqin Liang, Haixin Chang, Jingying Xu, Wenjuan Zhu
Předmět:
Zdroj: Nano Biomedicine & Engineering; 2012, Vol. 4 Issue 2, p76-82, 7p, 2 Black and White Photographs, 2 Diagrams, 5 Graphs
Abstrakt: In this paper, Tin (IV) oxide nanoparticles/graphene (SnO2/GR) nanocomposites were prepared via vacuum thermo treatment of Tin (0) and graphene oxide (GO). A redox reaction would occur readily in this process, in which the novel oxygen donor: GO could act as the oxidizing agent to oxidize Tin (0) to Tin (IV), meanwhile, the graphene precursor: GO would be simultaneously reduced to graphene by Tin (0) readily. The resulted composites were characterized by Fourier transform infrared spectrometry, scanning electron microscopy, and X-ray diffraction spectroscopy ect.. The novel SnO2/GR nanocomposites could combine both advantages of inorganic metal nanoparticles and graphene for near infrared spectroscopy (NIR) light absorption to generate heat, which fosters SnO2/GR a special candidate for photothermal ablation therapy (PTA) with NIR. Further investigations show that the SnO2/GR nanocomposites with NIR features could provide viable option for enhancing the thermal deposition and specificity of hyperthermia treatments for elimination of human prostate cancer (PC3). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index