| Autor: |
Foulds, George, Brennan, Doreen R., Wajszczuk, Charles, Catanzaro, Antonino, Garg, Dyal C., Knopf, William, Rinaldi, Michael, Weidler, Donald J. |
| Zdroj: |
Journal of Clinical Pharmacology; Apr1988, Vol. 28 Issue 4, p363-366, 4p |
| Abstrakt: |
One hour after intravenous doses of 50 mg/d fluconazole for 6 days or 100 mg/d for seven days to healthy subjects, the cerebrospinal fluid concentrations of fluconazole were 1.26 mg/L and 2.74 mg/L, respectively. These values were approximately 52% and 62% those of serum. Four patients with an initial clinical diagnosis of meningitis also had significant concentrations of fluconazole in the cerebrospinal fluid. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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