Mineral Dusts Oxidize Methionine Residues: Probable Mechanism of Inactivation of Alpha-1-Antitrypsin.

Autor: Li, K., Zay, K., Churg, A.
Předmět:
Zdroj: Annals of Occupational Hygiene; 1997 Inhaled Particles VIII, Vol. 41, p379-383, 5p
Abstrakt: The article discusses the mechanism of inactivation of alpha-1-antitrypsin (a1AT). Cigarette smoke has been believed that it inactivates a1AT by oxidizing methionine residues. Moreover, an observation has been done by testing whether mineral dusts can similarly oxidize methionine, either as a pure amino acid, or in whole proteins.
Databáze: Complementary Index