Optimization Approaches in the Routine Analysis of Monoclonal Anitbodies by Capillary Electrophoresis.

Autor: Salas-Solano, Oscar, Gennaro, Lynn, Felten, Chantal
Předmět:
Zdroj: LC-GC Asia Pacific; Feb2009, Vol. 12 Issue 1, p1-9, 9p
Abstrakt: The article focuses on a study, which evaluates monoclonal antibodies or protein based pharmaceuticals by implementing capillary electrophoresis (CE) in order to govern the overall quality control (QC) process at Genentech Inc., a biotechnology corp. It discusses the CE technologies like capillary electrophoresis sodium dodecyl sulphate (CE–SDS), capillary zone electrophoresis (CZE), and capillary isoelectric focusing (CIEF) that can potentially replace a slab gel format technology.
Databáze: Complementary Index