| Autor: |
NALMPANTIDIS, G., KAPETANOS, D., TALOUMTZIS, H., GAREFAS, A., GANTOS, A., KABA, R., HATZOPOULOS, E., POLYZOIS, D., TILKIRIDOU, A., PELTEKI, Z., AUGERINOS, A., MARIS, T., ILIAS, A. |
| Předmět: |
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| Zdroj: |
Archives of Hellenic Medicine / Arheia Ellenikes Iatrikes; Sep/Oct2012, Vol. 29 Issue 5, p606-613, 8p |
| Abstrakt: |
OBJECTIVE Prevalence estimation of spontaneous bacterial peritonitis (SBP) in inpatients and outpatients with cirrhosis of the liver in a tertiary care centre, and assessment of the diagnostic value of two types of reagent dipsticks (RD). METHOD Prospective study was made of consecutive patients with cirrhotic ascites and ⩾1 abdominal paracenteses who were enrolled over a 12-month period. Consecutive peritoneal fluid samples were analyzed with two types of RD (Aution 10A and Multistix® 10SG) and by microscopic examination (gold standard method), and the findings were compared. RESULTS A total of 108 samples were tested from 43 patients (31 men, 72.1%), with a median age of 70 years. The Child-Pugh classification was: A: 32.6%, B: 39.5%, C: 27.9%. The most common causes of liver cirrhosis were alcohol abuse, viral hepatitis and non-alcoholic steatohepatitis. SBP prevalence was 13.95% (95% CI: 5.80-28.62%). Sensitivity (Se) and specificity (Sp) were 83.33% and 95.56% for the Aution and 64.29% κal 100% for the Multistix, respectively. Positive (PPV) and negative predictive values (NPV) were 78.95% and 96.63% for the Aution and 100%, 92.42% for the Multistix, respectively. Accuracy (Ac) was 93.52% (Aution) and 93.33% (Multistix). In the follow-up, SBP samples Se, Sp, PPV, NPV and Ac were 90.90%, 81.80%, 83.30%, 90.00% and 86.00% for the Aution and 100%, 50.00%, 87.50%, 100% and 89.00% for the Multistix, respectively. CONCLUSIONS Approximately 1 in 7 patients with cirrhotic ascites was diagnosed with SBP. RD showed high diagnostic value in the rapid diagnosis and follow-up of SBP and satisfactory agreement in the total (κ=0.74) and SBP follow-up samples (κ=0.61). When using Multistix® 10SG, a positive result should be considered 2+ (125 leukocytes/μL). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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