| Autor: |
de Amorim Carvalho, Reinaldo, Arida, Ricardo Mario, Cavalheiro, Esper A. |
| Předmět: |
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| Zdroj: |
Epilepsia (Series 4); Feb2003, Vol. 44 Issue 2, p165-170, 6p |
| Abstrakt: |
Summary: Purpose: This study examined the effect of amygdala kindling development in Proechimys guayannensis rat, a common rodent of the Amazon basin. Methods: Adult male P. guayannensis animals (n = 43) and adult male Wistar rats (n = 14) were submitted to electrical amygdala kindling. Results: From 43 Proechimys rats submitted to the kindling process, only three animals reached stage 5 of kindling. During the kindling development (stages 4–5), these animals had behavioral alterations different from those observed in Wistar rats. A longer time spent in stages 1–3 and 5 and longer afterdischarge duration in stages 1–4 was observed in the Proechimys group compared with the Wistar group. The number of wet-dog shakes also was reduced in the Proechimys group during the kindling process. Conclusions: These findings suggest natural endogenous inhibitory mechanisms in this animal species. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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