| Autor: |
Litus, E., Zaitsev, V., Verovsky, V., Goncharova, L., Dudchenko, G., Ostrovskij, O. |
| Zdroj: |
Biochemistry (Biokhimiya). Supplemental Series B, Biomedical Chemistry; Jul2013, Vol. 7 Issue 3, p222-225, 4p |
| Abstrakt: |
The aim of this study was to determine the reference interval of serum cobalt-binding capacity (CoBC), and to estimate the effect of factors unrelated to oxidative modification of serum albumin on this diagnostic marker. Healthy volunteers ( n = 194), patients with autoimmune diseases ( n = 44) and patients with type 2 diabetes mellitus ( n = 50) were enrolled in the study. The regional reference interval was found to be 0,462-0,744 mmol Co/L of serum. The study of serum CoBC in patients with autoimmune pathology and type 2 diabetes mellitus has shown that the CoBC level strongly depends on the serum protein profile. Therefore, this test may be used to diagnose the ischemia, although other pathologies associated with changes in the ratio of blood protein fractions can also influence the serum CoBC level. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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