Screening for bipolar disorder in adolescents with the Mood Disorder Questionnaire - Adolescent version ( MDQ- A) and the Child Bipolar Questionnaire ( CBQ).

Autor:	Miguez, Melissa, Weber, Béatrice, Debbané, Martin, Balanzin, Dario, Gex‐Fabry, Marianne, Raiola, Fulvia, Barbe, Rémy P., Vital Bennour, Marylène, Ansermet, François, Eliez, Stephan, Aubry, Jean‐Michel
Předmět:	THERAPEUTICS BIPOLAR disorder BIPOLAR disorder in adolescence REPORTING of diseases EARLY diagnosis QUESTIONNAIRE on Resources & Stress AFFECTIVE disorders DIAGNOSIS
Zdroj:	Early Intervention in Psychiatry; Aug2013, Vol. 7 Issue 3, p270-277, 8p
Abstrakt:	Aim Screening instruments for bipolar disorders ( BDs) in children and adolescents have been developed recently. The present study examined performances of the French versions of the Mood Disorder Questionnaire - Adolescent version ( MDQ- A) and Child Bipolar Questionnaire ( CBQ) in a sample of in- and outpatients. Methods Seventy-six adolescents (age 13-18) and parents first completed the MDQ- A (adolescent and parent versions) and CBQ screening instruments. About 3 weeks later, they had a diagnostic interview with the Kiddie- Schedule for Affective Disorders and Schizophrenia - Present and Lifetime ( K- SADS- PL), and the adolescent MDQ-A self-report was completed a second time. Results Eight of 76 patients (10.5%) met K- SADS- PL diagnostic criteria for BD. Test-retest reliability of the adolescent MDQ- A self-report was moderate (kappa = 0.66), whereas agreement between adolescent and parent reports was poor (kappa = 0.07). Sensitivity and specificity of the MDQ- A with respect to K- SADS- PL were 75.0% and 57.4% for the adolescent version, and 87.5% and 63.2% for the parent version. Corresponding figures were 50.0% and 73.5% for the CBQ. All three screening instruments had low positive predictive values (17.1% for the MDQ- A adolescent version; 21.9% for the MDQ- A parent version; 18.2% for the CBQ), whereas negative predictive values were higher than 90%. Conclusions The present study points to modest performances of the MDQ- A and CBQ to detect BDs in adolescents, with diagnostic criteria for BD being unmet for a majority of patients who screened positive. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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