Abstrakt: |
Postprandial lipemia (PPL) is characterized by increasing of the triglycerides (TG) rich lipoproteins after a fatty meal. Although it is known that during the day as permanently exposed to postprandial hyperlipemia may be caused by development of various health problems, its effects on synthesis/secretion of adipokines and metabolic processes still remain unclear. The aims of this study were to determine the levels of fasting leptin, adiponectin, acylation stimulating protein (ASP), resistin, apelin-13 and chemerin as adipokines in health subjects according to grouping of low, medium and high PPL. Therefore, healthy 48 (24 women/24 men, age range of 18-45 years) volunteers were included in this study. After 12 hours fasting, their personal information, glucose and lipid parameters, the levels of adipokines (by ELISA methods) were determined and Oral Triglyceride Tolerance Test (OTTT) was performed. Then, both women and men were divided into as equal three groups with low, medium, high PPL (n=8), according to the values of area (AUCTG) calculated by using triglyceride levels at 0, 2nd, 4th and 6th hours and, the levels of adipokines were evaluated. Although the progressive decreasing levels of adiponectin, ASP in women, and adiponectin, ASP, chemerin in men, and the progressive increasing level of leptin in men were seen according to sequencing low to high PPL, they were was not statistically significant (p>0.05). In conclusion, it was suggested that the levels of postprandial lipemia could be influenced on different processes in woman and man and thus it may be benefit taken into gender difference to evaluate. [ABSTRACT FROM AUTHOR] |