| Autor: |
Kavan, P, Sochor, M, Nyc, O, Lochmann, O, Koutecky, J, Skala, P J, McClain, L K |
| Předmět: |
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| Zdroj: |
Bone Marrow Transplantation; 3/1/98, Vol. 21 Issue 5, p521, 3p |
| Abstrakt: |
Clostridium difficile (C. difficile) pseudomembraneous colitis was diagnosed in a 13-year-old boy with Hodgkin’s disease 3 months after autologous bone marrow transplantation. Hematopoiesis was fully reconstituted at the time. C. difficile infection occurred after gall bladder empyema had been treated conservatively with i.v. antibiotics and prophylactic 4-week administration of oral amoxicillin. C. difficile colitis was diagnosed early and intensive supportive therapy combined with administration of i.v. and subsequently oral vancomycin therapy failed. It is a phenomenon rarely seen and successful eradication of the clostridium infection was only achieved by a combination of higher dose vancomycin with metronidazole. During the post-colitis recovery the patient experienced a relapse of Hodgkin’s disease and died following further surgical intervention 137 days post-transplantation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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