| Autor: |
Spilliaert, Rémi, Gudmundsdóttir, Ágústa |
| Předmět: |
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| Zdroj: |
Marine Biotechnology; 1999, Vol. 1 Issue 6, p598, 10p |
| Abstrakt: |
A unique trypsinogen complementary DNA has been isolated from an Atlantic cod (Gadus morhua) cDNA library. Its predicted amino acid sequence contains 249 residues with a putative polypeptide of 227 residues. The distinctive features of this polypeptide, referred to as trypsin Y, are its low number of hydrogen-bond-forming residues, high content of Met and Pro residues, and lack of one conserved disulfide bond. Alignments show that cod trypsinogen Y has only approximately 45% identity to the two Atlantic cod tryp-sinogens I and X and most vertebrate trypsinogens. However, it has more than 70% identity to three other fish trypsinogens from two Pleuronectes and an Antarctic Notothenia species. These four trypsinogens share some unique characteristics and form a novel group, here referred to as group III. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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