| Autor: |
Lu, Weining, Fan, Xiaohong, Basora, Nuria, Babakhanlou, Hermik, Law, Terry, Rifai, Nader, Harris, Peter C., Perez-Atayde, Antonio R., Rennke, Helmut G., Zhou, Jing |
| Předmět: |
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| Zdroj: |
Nature Genetics; Feb99, Vol. 21 Issue 2, p160, 2p |
| Abstrakt: |
Characterizes autosomal dominant polycystic kidney disease due to PKD1 mutations through progressive appearance of renal, hepatic and pancreatic cysts in adults. Observation of cysts from the cortex and inner medulla; Development of scattered renals and hepatic cysts in Pkd[sup +/-] mice; Development of renal cysts and prenatal death in homozygotes due to targeted deletion of exon 34 in Pkd1. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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