Autor: |
Atmakur, Krishnaiah, Emmadi, Narender Reddy, Balasubramanian, Sridhar |
Předmět: |
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Zdroj: |
Journal of Heterocyclic Chemistry; May2013, Vol. 50 Issue 3, p513-518, 6p, 6 Diagrams |
Abstrakt: |
A series of novel fluorinated 11 H-azaindolo[3,2- c]isoquinolines ( 7) have been synthesized starting from 2(1 H)pyridones ( 1) via azaindoles ( 5). Initially, compound 1 was treated with POCl3/DMF, and the resulting compound 2 was reacted with benzylamine to obtain compounds 3 that were subjected to cyclization after protecting the secondary amine to get azaindoles ( 5). Further, compounds 5 were subjected to cyclization as per Pictet-Spengler reaction condition. However, it was not successful. Subsequently, the azaindoles ( 5) were acetylated and then cyclized to give title compounds 7. These compounds are new and well characterized by spectral data. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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