| Autor: |
Cruguel, Sébastien, Ferré-L'Hôtellier, Véronique, Morinière, Catherine, Lemerle, Sophie, Reynier, Pascal, Descamps, Philippe, May-Panloup, Pascale |
| Předmět: |
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| Zdroj: |
Journal of Assisted Reproduction & Genetics; Jun2013, Vol. 30 Issue 5, p683-690, 8p |
| Abstrakt: |
Purpose: The reduction of the number of embryos transferred while maintaining a satisfactory rate of pregnancy (PR) with in vitro fertilization calls for a refined technique of embryonic selection. This prospective study investigates the significance of early embryonic compaction at day 3 as a marker of the chances of implantation. Methods: We examined 317 transfers and their outcome involving 509 embryos including 91 compacted embryos. Results: Early compaction seems linked with the ovarian response to stimulation and embryonic quality. The PR is significantly increased when the embryonic cohort contains at least one compacted embryo (44 % versus 29.5 %, p = 0.01), and when at least one compacted embryo is transferred (44 % versus 31 %, p < 0.05). The analysis of our single embryo transfers shows that the implantation rates are significantly better for compacted embryos (50 % versus 30 %, p < 0.05) (OR 2.98; CI 1.02-5.28). Conclusion: Thus, early compaction, sometimes observed at day 3, may serve as a useful additional criterion for selecting the embryos transferred. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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