DOES A LEAN PREPREGNANCY BODY MASS INDEX INFLUENCE OUTCOME IN PREGNANCIES COMPLICATED BY MILD PREECLAMPSIA REMOTE FROM TERM?*.

Autor: Barton, John R., O'Nan, Jean M., Bergauer, Niki K., Jacques, Debbie L., Sibai, Baha M.
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Zdroj: Hypertension in Pregnancy; Nov2001, Vol. 20 Issue 3, p283-290, 8p, 4 Charts
Abstrakt: Objectives. To determine the influence of a lean prepregnancy body mass index (BMI) on pregnancy outcome in women with mild preeclampsia. Study Design. A matched cohort design was used. A total of 99 pregnant women with mild preeclampsia and a nonobese prepregnancy BMI (22-28 kg/m²) were matched 1:1 for gestational age at diagnosis, race, and parity to 99 women with mild preeclampsia, but a lean prepregnancy BMI (≤ 20 kg/m²). All patients were enrolled in an outpatient management program between 24 and 36 weeks' gestation for a minimum of 2 days, had singleton pregnancies, and exhibited proteinuria of ≥ 1 + at the start of the program. Outpatient monitoring included automated blood pressure measurements and daily assessment of weight, proteinuria, and fetal movement. Results. The mean gestational age at enrollment was 33.4 ± 2.8 weeks for both groups. By matching, 65% of patients in each group were nulliparous and 79% of patients in each group were of the white race. There were no patients in either group with a history of preterm delivery. The mean gestational age at delivery (36.8 ± 2.3 versus 36.3 ± 2.3 weeks, p = 0.047) was greater in the lean prepregnancy BMI group with a lower cesarean section rate (32% versus 52%, p = 0.006) but similar mean birth weights (2728 ± 698 versus 2679 ± 802 g, p = 0.635). There were two perinatal deaths in the lean prepregnancy BMI group and one in the nonobese prepregnancy BMI group (p = 1.0). Conclusion. In patients with mild preeclampsia remote from term, a lean prepregnancy BMI was associated with a later gestational age at delivery and a reduced incidence of cesarean delivery. Neonatal outcomes, however, did not differ significantly between the groups. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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