| Autor: |
Ananda, S., Ramananda, M., Made Gowda, N. |
| Předmět: |
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| Zdroj: |
Synthesis & Reactivity in Inorganic & Metal-Organic Chemistry; Oct2001, Vol. 31 Issue 9, p1631, 15p |
| Abstrakt: |
The kinetics of oxidation of chlorpromazine hydrochloride (CPH) and fluphenazine dihydrochloride (FPH) by bromamine-B (BAB) in pH 1.6 buffer solution has been studied spectrophotometrically at λmax = 570 nm and 530 nm, respectively. The reaction rate shows a fractional-order dependence on [BAB] and a first-order dependence on [CPH or FPH]. The reaction rate also shows a fractional-order dependence on [H+]. Additions of halide ions and the reduction product of BAB, benzenesulfonamide, and variation of the ionic strength and dielectric constant of the medium do not have any significant effect on the reaction rate. The reaction was studied at different temperatures and activation parameters were evaluated. The proposed general mechanism and the derived rate law are in agreement with the observed kinetics. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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