Angiosarcoma of the parotid gland with a t(12;22) translocation creating a EWSR1-ATF1 fusion: a diagnostic dilemma.

Autor: Gru, Alejandro Ariel, Becker, Nils, Pfeifer, John D
Předmět:
Zdroj: Journal of Clinical Pathology; May2013, Vol. 66 Issue 5, p452-454, 3p, 3 Color Photographs
Abstrakt: The article describes the case of a 72-year-old woman who presented with a six-week history of rapidly enlarging mass of her right jaw with associated facial nerve paralysis. A malignant tumour of the parotid gland was originally thought to represent metastatic melanoma which was reclassified as malignant melanoma of soft part/clear cell sarcoma (MMSP/CCS) on the basis of the presence of a EWSRI-ATF1 gene fusion. A diagnostic dilemma ended with a hybrid diagnosis of angiosarcoma with MMSP/CCS.
Databáze: Complementary Index