Quantifying the shifts in physicochemical property space introduced by the metabolism of small organic molecules.

Autor: Kirchmair, Johannes, Howlett, Andrew, Peironcely, Julio, Murrell, Daniel S., Williamson, Mark, Adams, Samuel E., Hankemeier, Thomas, van Buren, Leo, Duchateau, Guus, Klaffke, Werner, Glen, Robert C.
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Zdroj: Journal of Cheminformatics; 2013, Vol. 5 Issue S1, p1-2, 2p, 1 Graph
Abstrakt: A conference paper about the metabolic analysis of small organic molecules and shift quantification of physicochemical property space introduced by them is presented. It states that the study investigates the difference between the molecules of metabolic product form their parent molecule. The result suggests new approaches to utilize metabolism analysis as a way for the development of new drugs and cosmetics.
Databáze: Complementary Index