Vitamin D levels in Malawian infants from birth to 24 months.

Autor: Amukele, Timothy K., Soko, Dean, Katundu, Pauline, Kamanga, Melvin, Sun, Jin, Kumwenda, Newton I., Taha, Taha E.
Předmět:
Zdroj: Archives of Disease in Childhood; Mar2013, Vol. 98 Issue 3, p180-183, 4p, 3 Charts
Abstrakt: We measured longitudinal levels of vitamin D in unsupplemented Malawian infants at 0 (birth), 2, 12, 15, 18 and 24 months of age. Matched maternal plasma and breast milk vitamin D2 and D3 levels were also measured at delivery and 2 months postpartum. Vitamin D was measured using isotope-dilution liquid chromatography tandem-mass spectrometry. Vitamin D3 levels in children were 36% of adult levels at birth, 60% of adult levels at age 2 months, and at par with adult levels by 12 months of age. This adult-equivalent level is subsequently maintained through age 24 months and consisted of a 98% molar ratio of vitamin D3. Vitamin D levels in breast milk were below the limit of detection, 0.1 ng/ml. Breast milk of unsupplemented Malawian mothers is a poor source of vitamin D. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index