Digital Chromoendoscopy for Diagnosis of Diminutive Colorectal Lesions.

Autor: dos Santos, Carlos Eduardo Oliveira, Malaman, Daniele, Lopes, César Vivian, Pereira-Lima, Júlio Carlos, Parada, Artur Adolfo
Předmět:
Zdroj: Diagnostic & Therapeutic Endoscopy; 2012, p1-7, 7p, 2 Color Photographs, 1 Diagram, 4 Charts
Abstrakt: Introduction. To compare the accuracy of digital and real-time chromoendoscopy for the differential diagnosis of diminutive (<5mm) neoplastic and nonneoplastic colorectal lesions. Materials and Methods. This is a prospective randomized study comparing the Fujinon intelligent color enhancement (FICE) system (65 patients/95 lesions) and indigo carmine (69 patients/120 lesions) in the analysis of capillary meshwork and pit pattern, respectively. All lesions were less than 5 mm in diameter, and magnification was used in both groups. Histopathology was the gold standard examination. Results. Of 215 colorectal lesions, 153 (71.2%) were adenomas, and 62 were hyperplastic polyps (28.8%).Morphological analysis revealed 132 (61.4%) superficial lesions, with 7 (3.3%) depressed lesions, and 83 (38.6%) protruding lesions. Vascular meshwork analysis using FICE and magnification resulted in 91.7% sensitivity, 95.7% specificity, and 92.6% accuracy in differentiating neoplastic from nonneoplastic lesions. Pit pattern analysis with indigo carmine and magnification showed 96.5% sensitivity, 88.2% specificity, and 94.2% accuracy for the same purpose. Conclusion. Both magnifying virtual chromoendoscopy and indigo carmine chromoendoscopy showed high accuracy in the histopathological diagnosis of colorectal lesions less than 5mm in diameter. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index