| Autor: |
Sun, Shengai, Yu, Rilei, Zhang, Yanhui, Li, Yanni |
| Zdroj: |
Frontiers of Chemical Engineering in China; Sep2010, Vol. 4 Issue 3, p348-352, 5p |
| Abstrakt: |
A mouse muscle type nAChR model ((α1)βδδg) was built based on the cryoelectron microscopic structure of intact Torpedo marmorata nAChR and the high resolution crystal structure of nAChR-α1 subunit. The conformation of the pentameric nAChR model was investigated by molecular dynamic simulation. The function of water molecule in the hydrophilic interior was clarified. The reason for Tyr127 showing two alternative conformations was discussed in detail. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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