Autor: |
Cheraiet, Zinelaabine, Ouarna, Souad, Hessainia, Sihem, Berredjem, Malika, Aouf, Nour-Eddine |
Předmět: |
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Zdroj: |
ISRN Organic Chemistry; 2012, p1-8, 8p |
Abstrakt: |
A simple, efficient, and eco-friendly protocol for the N-Boc protection of the amine moiety in a variety of compounds with di-tert-butyl dicarbonate under water-acetone catalyst-free conditions is described. The corresponding monocarbamate is obtained in excellent yields on short reaction times. No competitive side reactions such as isocyanate urea and O-Boc were observed. This method represents a reasonable alternative to the previous reported protection procedures. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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