| Autor: |
Halling, Jónrit, Petersen, Maria Skaalum, Jørgensen, Niels, Jensen, Tina Kold, Grandjean, Philippe, Weihe, Pál |
| Zdroj: |
BMJ Open; Mar2013, Vol. 3 Issue 3, Special section p1-11, 30p |
| Abstrakt: |
Objectives: To determine semen quality and reproductive hormone levels in young Faroese men. Design: Descriptive cross-sectional study of Faroese men compared with Danish men. Setting: Faroese one-centre study. Participants: 481 men born from 1981 to 1987 and investigated from 2007 to 2010. Outcome measures: Sperm concentration, semen volume, total sperm count, sperm motility, sperm morphology and reproductive hormone levels. Results: Sperm concentrations for the Faroese men were lower than for the Danish men (crude median 40 vs 48 mill/ml, p<0.0005). Semen volume was higher, and thus the total sperm counts did not differ (159 vs 151 mill, p=0.2). Motility and morphology did not differ between the Faroese and Danes. The inhibin B/follicle-stimulating hormone ratios for the Faroese men were lower than for the Danes (64 vs 76, p=0.001). Similarly, lower total testosterone/luteinising hormone (LH) ratio (4.6 vs 6.0, p<0.0005) and lower calculated free-testosterone/LH ratio (94 vs 134, p<0.0005) were detected for the Faroese men. Conclusions: Semen quality among the Faroese men is at the same low level as reported for Danish men, and the reproductive hormone levels furthermore indicated a lower Leydig cell capacity for testosterone production. The influence of environmental exposure and genetic factors on semen quality has to be studied further. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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