Multiple mutations are common at mouse Aprt in genotoxin-exposed mismatch repair deficient cells.

Autor:	Shin, Chi Y., Mellon, Isabel, Turker, Mitchell S.
Předmět:	MUTAGENS DNA repair CELL lines
Zdroj:	Oncogene; 3/7/2002, Vol. 21 Issue 11, p1768, 9p, 2 Diagrams, 5 Charts
Abstrakt:	Presents a study that examined mutagenic events at the mouse Aprt gene in kidney cell lines derived from mice deficient for the PMS2 and MLH1 mismatch repair proteins. Impact of mismatch repair deficiency on mutations; Characteristics of mutator phenotypes; Background on DNA mismatch repair.
Databáze:	Complementary Index
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