Near-infrared fluorescence sentinel lymph node biopsy in vulvar cancer: a randomised comparison of lymphatic tracers.

Autor:	Schaafsma, BE, Verbeek, FPR, Peters, AAW, Vorst, JR, Kroon, CD, Poelgeest, MIE, Trimbos, JBMZ, Velde, CJH, Frangioni, JV, Vahrmeijer, AL, Gaarenstroom, KN
Předmět:	COMPUTER-assisted surgery VULVAR cancer INDOCYANINE green SERUM albumin SENTINEL lymph nodes
Zdroj:	BJOG: An International Journal of Obstetrics & Gynaecology; May2013, Vol. 120 Issue 6, p758-764, 7p, 1 Color Photograph, 1 Diagram, 2 Charts
Abstrakt:	This study aims to confirm the feasibility of near-infrared ( NIR) fluorescence imaging for sentinel lymph node ( SLN) biopsy in vulvar cancer and to compare the tracer indocyanine green ( ICG) bound to human serum albumin ( HSA) versus ICG alone. Women received 99mTc-nanocolloid and patent blue for SLN detection. Subsequently, women randomly received ICG: HSA or ICG alone. In 24 women, 35 SLNs were intraoperatively detected. All SLNs detected were radioactive and NIR fluorescent and 27 (77%) were blue. No significant difference was found between ICG: HSA and ICG alone. This trial confirms the feasibility of NIR fluorescence imaging for SLN mapping in vulvar cancer. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Plný text