Synthesis and bioassay of benzimidazole conjugates with adamantane.

Autor: Nurieva, E., Beloglazkyna, A., Shishov, D., Gogol, V., Glazkova, Ya., Wobith, B., Zefirov, N., Kuznetsov, S., Zefirova, O.
Zdroj: Moscow University Chemistry Bulletin; Jan2013, Vol. 68 Issue 1, p37-40, 4p
Abstrakt: The synthesis of 2-adamantyl-6-[(1 H-benzimidazol-1-ylcarbonyl)amino]hexanoate and 2-adamantyl-7-(1 H-benzimidazol-1-yl)-7-oxo-heptanoate, and the results of their cytotoxicity assay against human lung carcinoma cells A549 are presented in the paper. The impossibility of adding 5-(2-adamantyloxycarbonyl)pentyl isocyanate to nocodazole under various conditions was shown. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index