N-myc oncogene overexpression down-regulates IL-6; evidence that IL-6 inhibits angiogenesis and suppresses neuroblastoma tumor growth.

Autor: Hatzi, Elissavet, Murphy, Carol, Zoephel, Andreas, Rasmussen, Heidi, Morbidelli, Lucia, Ahorn, Horst, Kunisada, Keita, Tontsch, Ulrike, Klenk, Michael, Yamauchi-Takihara, Keiko, Ziche, Marina, Rofstad, Einar K., Schwiegerer, Lothar, Fotsis, Theodore
Předmět:
Zdroj: Oncogene; 5/16/2002, Vol. 21 Issue 22, p3552, 10p, 1 Chart, 5 Graphs
Abstrakt: Presents a study which reported that N-Myc overexpression results in down-regulation of interleukin-6 and that IL-6 is an inhibitor of endothelial cell proliferation and VEGF-induced rabbit corneal angiogenesis. Methodology; Results of the study; Conclusion.
Databáze: Complementary Index