Single-layer “domino” diodes via optofluidic lithography for ultra-low Reynolds number applications.

Autor: Sochol, Ryan D., Glick, Casey C., Lee, Kye Y., Brubaker, Thomas, Lu, Albert, Wah, Melissa, Gao, Shan, Hicks, Erica, Wolf, Ki Tae, Iwai, Kosuke, Lee, Luke P., Lin, Liwei
Zdroj: 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS); 1/ 1/2013, p153-156, 4p
Abstrakt: Autonomous fluidic components are critical to the advancement of integrated micro/nanofluidic circuitry for lab-on-a-chip applications, such as point-of-care (POC) molecular diagnostics and on-site chemical detection. Previously, a wide range of self-regulating microfluidic components, such as fluidic diodes, have been developed; however, achieving effective functionality at ultra-low Reynolds number (e.g., Re < 0.05) has remained a significant challenge. To overcome this issue, here we introduce single-layer microfluidic “domino” diodes, which utilize free-standing rotational microstructures — constructed in situ via optofluidic lithography — in order to passively regulate the fluidic resistance based on the flow polarity, thereby enabling flow rectification under ultra-low Re conditions. COMSOL simulation results revealed a theoretical Diodicity (Di) of 31 for a singular domino diode component. Experimental results (for systems with four microstructures) revealed Di's ranging from 13.0±1.9 to 25.4±1.9 corresponding to 0.025 < Re < 0.030 and 0.010 < Re < 0.015 flow, respectively, which represent the largest Di's reported for Re < 0.05 fluid flow. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index