| Abstrakt: |
The e-carboline compound and evodiamine were synthesized with improved Bischler-Napieralski-type and Diels-Alder-type reactions by taking tryptamine and N-methyl anthranilic acid as starting materials, enjoying the characteristics of few steps, simple ness, mild reaction conditions, high productivity and less pollution etc. Conduct elementary analyses on the resulting compounds and characterize them with analyzing means such as IR, ESI-MS, 1H NMR and 13C NMR. In addition, regular MTT cytotoxicity tests were also performed, and three different time periods were formulated to determine its IC50. [ABSTRACT FROM PUBLISHER] |
