Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man.

Autor: Nathrath, Michaela H., Kuosaite, Virginija, Rosemann, Michael, Kremer, Marcus, Poremba, Christopher, Wakana, Shigeharu, Yanagi, Masayuki, Nathrath, Walter B.J., Hofler, Heinz, Imai, Kenji, Atkinson, Michael J.
Předmět:
Zdroj: Oncogene; 8/29/2002, Vol. 21 Issue 38, p5975, 6p, 5 Diagrams
Abstrakt: Presents a study that compared allelic imbalances in human and murine osteosarcomas to identify genetic changes critical for osteosarcomagenesis. Background on osteosarcoma; Comparison between the human and mouse syntenic regions; Information on the association of disturbances of developmental control genes with tumorigenesis.
Databáze: Complementary Index