| Autor: |
Cheney, Philip P., Stachler, Michael D., Knowles, Michelle K. |
| Zdroj: |
2012 Annual International Conference of the IEEE Engineering in Medicine & Biology Society; 1/ 1/2012, p3159-3162, 4p |
| Abstrakt: |
P-glycoprotein transports chemotherapy drugs from the plasma membrane and allows cancer cells to survive treatment. We transiently transfected PGP labeled with enhanced green fluorescent protein (PGP-EGFP) into MES-SA cells and used single molecule tracking techniques to characterize the dynamics on the surface of live cells. PGP exhibits freely diffusive behavior at short times and is confined at long times with a transition to anomalous diffusion at 0.7 s. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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