The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer.

Autor: Daly, Roger J., Haihua Gu, Parmar, Jayamala, Malaney, Suzann, Lyons, Ruth J., Kairouz, Rania, Head, Darren R., Henshall, Susan M., Neel, Benjamin G., Sutherland, Robert L.
Předmět:
Zdroj: Oncogene; 8/1/2002, Vol. 21 Issue 33, p5175, 7p, 1 Color Photograph, 2 Black and White Photographs, 1 Graph
Abstrakt: Presents a study that investigated the marked overexpression of Grb2-associated binder 2 in a subset of breast cancer cell lines relative to normal breast epithelial strains. Background on steroid hormones; Details on the development and progression of human breast cancer; Importance of gab proteins in receptor kinases tyrosine kinases signaling.
Databáze: Complementary Index