Deregulated DNA polymerase β strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities.

Autor: Frechet, Mathilde, Canitrot, Yvan, Bieth, Anne, Dogliotti, Eugenia, Cazaux, Christophe, Hoffmann, Jean-Sebastien
Předmět:
Zdroj: Oncogene; 4/4/2002, Vol. 21 Issue 15, p2320, 8p, 1 Diagram, 5 Graphs
Abstrakt: Presents a study on the action of deregulated DNA polymerase β on ionizing radiation-induced nucleotidic and chromosomal instabilities. Role of DNA synthesizing enzymes as source of genomic alterations; Improvement of ionizing radiation-induced DNA breaks by deregulated polymerase β; Materials and methods.
Databáze: Complementary Index