| Autor: |
Gunasekaran, S., Vijay, T., Sarumathy, K., Palani, S., Panneerselvam, R. P. S., Srinivasan, V. |
| Předmět: |
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| Zdroj: |
International Journal of Pharmacy & Life Sciences; Feb2013, Vol. 4 Issue 2, p2380-2386, 7p |
| Abstrakt: |
Grewiaum bellifera is an Indian traditional medicinal plant of the Tiliaceae family. The aerial plant part extract is much more useful in treatment like spleen damage, liver complications and cardio disorders. The rats were treated orally with the extract of Grewiaumbellifera at 250mg and 500 mg / kg body wt.for 28days. Biochemical parameters viz. fasting blood glucose, blood urea, serum creatinine and total cholesterol were analyzed. Phytocontituents like Triterpene, Asarone, Diterpene, linoleic acid ester, Flavonoid compound, Steroid compound were present in GCMS analysis. It was also observed that fasting blood glucose showed a significant decrease at a dose of 500mg/kg body wt. (From 280.8 ± 2.29 to 118.8 ± 3.99mg/dl) when compared with that of standard drug glibenclamide. The results shows in this study clearly indicates that the extract possess anti-hyperglycemic activity and may be promising for the development of phytomedicine for diabetes mellitus. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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