Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-β[sub1]-dependent pathway.

Autor: Xiao-Hua Jiang, Shiu-Kum Lam, Lin, Marie C.M., Shi-Hu Jiang, Hsiang-Fu Kung, Slosberg, Eric D., Jae Won Soh, Weinstein, I. Bernard, Chun-Yu Wong, Benjamin
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Zdroj: Oncogene; 9/5/2002, Vol. 21 Issue 39, p6113, 10p, 6 Graphs
Abstrakt: Provides information on a study which examined the effects and possible molecular target of a specific cyclo-oxygenase-2 (COX-2) inhibitor in gastric cancer. Utilization of nonsteroidal anti-inflammatory drugs in patients with gastrointestinal cancers; Mechanism of COX-2 inhibitors; Discussion of the process of apoptosis and cancer cell growth.
Databáze: Complementary Index