Effects of combinations of amino acids on cell proliferation in tissue culture of old rats.

Autor: Chalisova, N., Kontsevaya, E., Zhekalov, A., Sinyachkin, D.
Zdroj: Advances in Gerontology; Jan2013, Vol. 3 Issue 1, p77-79, 3p
Abstrakt: In organotypic tissue culture, we studied the effects of combinations of a standard amino acid at an effective concentration of 0.05 ng/mL on cell proliferation processes in explants of the spleen, myocardium, pancreas, and cerebral cortex from 24-month-old rats. Combinations of two amino acids, one of which stimulated proliferation while the other inhibited it, induced the proliferation of cells in tissue culture. These effects were 8-10% higher than that of stimulating the amino acid. These data may be used to develop new effective dipeptides, which can be used to improve regenerative tissue capabilities during aging. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index