Serial serum zinc levels in preterm infants during parenteral and enteral feedings.

Autor: Vileisis, Rita A., Deddish, Ruth B., Fitzsimons, Edward, Hunt, Carl E.
Předmět:
Zdroj: American Journal of Clinical Nutrition; Dec1981, Vol. 34 Issue 12, p2653-2657, 5p, 1 Chart, 1 Graph
Abstrakt: Weekly serum zinc levels during the neonatal period have been obtained in 17 preterm infants randomly assigned to a prospective feeding study. Nine neonates received a standard regimen of naso-jejunal feedings (group I) and eight matched infants received total parenteral nutrition (group II) for the first 2 wk, followed by enteral intake for the last 2 wk of the study period. No patient received supplemental zinc intake. Base-line serum zinc levels obtained before beginning feedings at 2 days of age were in the normal range and not significantly different, 121 ± 15 and 135 ± 8 μg/dl in groups I and II, respectively (mean ± SEM). Serial serum zinc levels decreased progressively in both groups during the 4-wk study period, reaching a low of 80 ± 7 μg/ dl in group I and 85 ± 10 μg/dl in group II. The progressive decline in serum zinc levels is postulated to be indicative of tissue depletion of zinc. Our data suggest that preterm infants fed either by short-term total parenteral nutrition or by transpyloric enteral feedings are at risk for marginal zinc deficiency states. [ABSTRACT FROM AUTHOR]
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